Lantern Pharma Completes Patient Enrollment in Japan for Phase 2 HARMONIC(TM) Trial Targeting Never-Smoker NSCLC

By Trinzik

TL;DR

Lantern Pharma's LP-300 trial in Japan offers a strategic advantage in targeting never-smoker NSCLC, a market with high unmet needs and limited competition.

LP-300 is tested with standard chemotherapy in relapsed NSCLC patients after tyrosine kinase inhibitor therapy, focusing on Japan's high never-smoker incidence.

This trial could significantly improve treatment options for never-smoker NSCLC patients, addressing a critical gap in oncology care and enhancing global health outcomes.

Lantern Pharma leverages AI to fast-track LP-300 development, targeting never-smoker NSCLC in Japan, with additional trial data expected from Taiwan and the U.S. by Q3 2025.

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Lantern Pharma Completes Patient Enrollment in Japan for Phase 2 HARMONIC(TM) Trial Targeting Never-Smoker NSCLC

Lantern Pharma (NASDAQ: LTRN) has reached a significant milestone by completing targeted patient enrollment in Japan for its ongoing Phase 2 HARMONIC(TM) clinical trial. The trial is evaluating the investigational drug candidate LP-300 in never-smoker non-small cell lung cancer (NSCLC) patients, a demographic with notably limited treatment options. Japan's high incidence of never-smoker NSCLC positions it as a strategic location for this trial, which aims to address the unmet needs of this specific patient group.

The company successfully enrolled 10 patients across five sites in Japan, including the prestigious National Cancer Center in Tokyo, ahead of its internal schedule. This achievement not only demonstrates Lantern Pharma's commitment to accelerating the development of therapies for underserved cancer markets but also underscores the potential of its AI-driven approach to identify and prioritize drug candidates more efficiently. LP-300 is being tested in combination with standard chemotherapy agents, targeting patients who have relapsed after tyrosine kinase inhibitor therapy.

Additional trial data from Taiwan and the U.S. is anticipated later in the third quarter of 2025, which could provide further insights into the efficacy and safety of LP-300. Lantern Pharma's innovative use of artificial intelligence and machine learning in oncology drug development represents a promising avenue for addressing complex challenges in cancer treatment, particularly for patient populations that have been historically overlooked.

For more information on Lantern Pharma's groundbreaking work, visit https://ibn.fm/JXFqG. The company's progress in the HARMONIC(TM) trial not only highlights the potential of LP-300 but also the importance of leveraging technology to tailor cancer therapies to specific genetic and environmental factors, offering hope to never-smoker NSCLC patients worldwide.

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Trinzik

Trinzik

@trinzik

Trinzik AI is an Austin, Texas-based agency dedicated to equipping businesses with the intelligence, infrastructure, and expertise needed for the "AI-First Web." The company offers a suite of services designed to drive revenue and operational efficiency, including private and secure LLM hosting, custom AI model fine-tuning, and bespoke automation workflows that eliminate repetitive tasks. Beyond infrastructure, Trinzik specializes in Generative Engine Optimization (GEO) to ensure brands are discoverable and cited by major AI systems like ChatGPT and Gemini, while also deploying intelligent chatbots to engage customers 24/7.