Sino Biological, Inc. (Shenzhen Stock Exchange: 301047.SZ) has announced the launch of its XPressMAX™ Cell-Free Protein Synthesis Kit (Cat#: CFKIT02), a new tool designed to accelerate AI-driven high-throughput screening for antibody drug discovery. The kit leverages cell-free protein synthesis technology to produce target proteins and antibodies in vitro within three hours, bypassing the limitations of traditional cell-based expression systems.
According to the company, the XPressMAX™ kit is based on an E. coli lysate and is fully supplemented with essential transcription and translation components, enabling direct protein synthesis from plasmid or PCR templates. It is specifically designed for antibody drug discovery and supports the rapid expression and validation of VHH, scFv, Fab, and miniproteins. Sino Biological has established a high-throughput cell-free expression platform that can validate over 2,000 scFv/VHH molecules in three to four weeks, matching the rapid iteration demands of AI-driven screening.
Key highlights of the kit include ultra-fast synthesis completed in just three hours, a success rate greater than 99%, and support for complex disulfide bonding without additional enhancers, ensuring native folding and bioactivity. Dr. Rob Burgess, Chief Business Officer at Sino Biological US, Inc., stated, "Our XPressMAX™ is a significant advancement in research tools and reagents for next-generation therapeutic discovery. By combining rapid, reliable protein expression with intelligent screening, we are helping our partners compress antibody discovery timelines without compromising quality."
Dr. Jie Zhang, Sino Biological’s General Manager, added, "AI is revolutionizing antibody screening, but it demands expression systems that can match its speed and throughput. XPressMAX™ achieves rapid, high-success expression of challenging proteins in as little as 3 hours." The kit is expected to reduce both development timelines and costs by seamlessly integrating with AI-powered screening platforms.
Researchers can visit Sino Biological's website to explore more about XPressMAX™ or request a free sample. Sino Biological, headquartered in Houston, Texas, is an international reagent supplier and CRO service provider specializing in recombinant protein production and antibody development. The company serves researchers in over 90 countries and maintains a stringent quality management system across all products.
